Angela Denoke appears regularly with the opera houses of Vienna, New York, Paris, London, Munich, Madrid and Barcelona, as well as the Salzburger Festspiele and the Berliner Philharmoniker, the Symphonieorchester des Bayerischen Rundfunks, Philharmonia Orchestra, London Symphony Orchestra and the Boston Symphony Orchestra. Her recordings include Vec Makropulos, Salome, Alceste, a New Year’s Eve Lehár Gala (Staatskapelle Dresden with Christian Thielemann), Die tote Stadt, Die Walküre, Kátya Kabanová, Cardillac, Beethoven Symphony No.9 (with Mikhail Pletnev as well as Daniel Barenboim), Wozzeck (with Ingo Metzmacher) and Fidelio (with Sir Simon Rattle).
Her jazz and chanson programme »From Babelsberg to Beverly Hills«, devoted to the era of Marlene Dietrich and Zarah Leander, has toured throughout Europe. Her Kurt Weill recital »Two Lives to Live« was premiered at the 2011 Salzburger Festspiele and toured venues including the Wiener Staatsoper and the Gran Teatre del Liceu, Barcelona. Her latest recital programme »Städtebewohner, Kurt Weill und seine Zeit« premiered at the 2015 Salzburger Festspiele.
She was voted Singer of the Year by Opernwelt in 1999 and in 2007 received the Deutsche Theaterpreis Der Faust for her portrayal of Salome. In February 2009 the Austrian Government awarded her the title of Kammersängerin of the Wiener Staatsoper.